The pandemic is projected to cost the US almost $8 trillion over the next 10 years. It isn’t alone, unfortunately. No country will be immune from the toll. Knowing the cost, as well as the complexity, how can we think our way through this to optimize the ability to resume work and education, but not at the price of compromised health? Where should we be investing to build back better and healthier? Is our choice really, as some argue, between a robust economy and investing in health?